Leslie Jones will headline the voice cast of the adult animated comedy, which is under development by Warner Bros. Animation.
The actor will also serve as the executive producer of the series, which has her voice the lead character called Plastic.
With no writer or director attached to the project, the plot details and title are also kept under wraps.
Leslie, who has acted in films like Coming 2 America and Ghostbusters, also has a stellar work in television, which includes credits in shows like Saturday Night Live, Our Flag Means Death and Workaholics.